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Contact Information:

Alyssa Burke

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631-840-3185

Release Date:

November 09, 2023

Bio-Botanica® announces Puresterol® (pueraria mirifica) based serums found to reduce wrinkles in clinical trials

Hauppauge, N.Y., November 9, 2023 – Bio-Botanica, Inc., ® the one American company that has manufactured botanical extracts under one family for more than 50 years, has revealed the results of clinical trials indicating its proprietary botanical extract ingredient, Puresterol® (Pueraria mirifica), showed positive effects on the reduction of wrinkles when used in a face serum.
Pueraria mirifica grows only in the rich soils of the high-altitude rainforests of Thailand and has been used by the Thais for a millennium as a rejuvenator and revitalizer to help offset some of the effects of aging. Puresterol®, developed by Bio-Botanica, is the only patented, specially processed and highly active compound of Pueraria mirifica available in the market today (US Patent # 7,658,955, 2023).
A third-party contract research organization (CRO) conducted clinical trials of Puresterol® in two different serum formulations under sponsorship by Bio-Botanica. In each trial, 21 subjects in different groups applied a serum in the morning and night for 28 days. The CRO used a state-of-the-art 3D structured-light scanner and software to precisely measure the area, length, and depth of crow’s feet and forehead wrinkles at day 0 and day 28. In addition, subjects were asked to evaluate their assessment of their treatment.
The first, placebo-controlled trial indicated Puresterol® in a serum had a statistically significant greater reduction of the depth of Crow’s feet wrinkles when compared to placebo (p<0.05). The Puresterol® containing serum reduced the area of Crow’s feet wrinkles (p<0.01), the length of Crow’s feet wrinkles (p<0.01), and the depth of forehead wrinkles (p<0.01) from day 0 to day 28 in a statistically significant manner. 1 A follow up study with a different amount of Puresterol® in a serum indicated similar results with a statistically significant reduction in area of Crow’s feet wrinkles (p<0.05), length of Crow’s feet wrinkles (p<0.0001) and area of forehead wrinkles (p<0.05) from day 0 to day 28. 2 Additionally, over 80% of subjects in each of the Puresterol® groups indicated that at day 28, the Puresterol® based serum left the contours of their face appearing smoother. These results support a previous in vitro trial sponsored by Bio-Botanica® which found varied concentrations of Puresterol® inhibited Collagenase activity accordingly.3 Collagenase is an enzyme known to break down collagen and elastin and possibly lead to wrinkle formation.
Bio-Botanica® is a family-owned and operated company, specializing in botanical extracts since its founding in 1972. Bio-Botanica® is a leading manufacturer of high-quality botanical extracts for personal care/cosmetics, food and beverage, flavor/fragrance, supplements, and dietary supplement industries. Located in Hauppauge, New York, Bio-Botanica’s ® 160,00 square foot botanical extraction facility houses its own R&D, Microbiological, and QC laboratories. It has a state-of-the-art facility and experienced staff who work together on every project ensuring that Bio-Botanica ® successfully meets customer goals and objectives.

About Bio-Botanica, Inc.

Bio-Botanica® is a family-owned and operated company, specializing in botanicals extracts since its founding in 1972. Bio-Botanica® is a leading manufacturer of high-quality botanical extracts for personal care/cosmetics, food and beverage, flavor/fragrance, supplements, and nutraceutical industries. Located in Hauppauge, New York, Bio-Botanica’s ® 160,00 square foot botanical extraction facility houses its own R&D, Microbiological, and QC laboratories. It has a state-of-the-art facility and experienced staff who work together on every project ensuring that Bio-Botanica ® successfully meets customer goals and objectives.

Media Contact:

Alyssa Burke

[email protected]

631-840-3185

Botanical Extracts Manufacturing | Manfacture botanical extracts for supplements.
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